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728 This method is particularly valuable for creating mitochondrial disease-associated cell lines and animal models, deepening our understanding of mitochondrial disorders and providing potential avenues for correcting both homoplasmic and heteroplasmic pathogenic variants

There are no specific severe symptoms, but common symptoms such as a rapid heart rate and breathing, gastrointestinal symptoms, and shivering How long do withdrawal symptoms last

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Since then, the understanding of LDNs has been expanded

36,37 thus, the TGF/Smad signaling pathway has been a prime target for antifibrotic therapy

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