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Meguro, S., Tomita, M., Katsuki, T., Kato, K., Oh, H., Ainai, A., et al., Int J

5-Amino-1-methylquinolinium iodide is the lead first-in-class small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT) an enzyme overexpressed in white adipose tissue of obese individuals where it consumes the methyl-donor pool and depletes tissue NAD

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