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When administered together, their mechanisms converge to amplify appetite regulation, energy intake reduction, and glycemic improvements, exceeding the individual effects of monotherapy by acting on complementary neuroendocrine circuits regulating body weight and metabolism 1-3

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DURATION-5: exenatide once weekly resulted in greater improvements in glycemic control compared with exenatide twice daily in patients with type 2 diabetes

Winning this recompete reflects our success, and we are eager to explore new opportunities, including the integration of artificial intelligence, in the next phase of this partnership. Over the next five years, REI will continue to innovate and improve the DSIP platform