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Given that enzymes other than DHAR may also contribute to GSH oxidation under oxidative stress conditions (Figure 6), the relatively low capacity of GR may be important to allow GSSG accumulation to fulfil signaling functions
[DOI] [PubMed] [Google Scholar] 323
41 In the presence of GST and reduced GSH, pesticides diazinon and diazoxon undergo conjugation to form S-(2-isopropyl-4-methylpyrimidin-6-yl)glutathione
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Oxidative stress in Alzheimers disease
