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Pretreatment of mice with either grape seed extract (100 mg/kg/day for 7 days) or green tea extract (0.25% - 1% of diet for 5 days) protected livers from acetaminophen-mediated damage, as determined by serum levels of ALT and microscopic examination (Bagchi 2002

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Consisting of dimeric transcription factors such as Jun and Fos, AP-1 binds to DNA motifs, such as TPA-responsive element (TRE) and cAMP-responsive element (CRE), initiating transcription of genes critical for cell survival and stress adaptation 73,74

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3.1.2 Other PEDs This group included other substances prohibited by WADA, such as non-approved substances (BPC-157) from Section S0, other anabolic agents (clenbuterol and SARMs) from Subsection S0, S1.2, peptide hormones and their releasing factors (AOD-9604, hGH 176-191, CJC-1295, ibutamoren, ipamorelin, and growth hormone-releasing peptide) from S2.2, growth factors and growth factor modulators (thymosin-4 and its derivative TB-500) from S2.3, beta-2 agonists (salbutamol and indacaterol) from S3, metabolic modulators (meldonium, GW1516, SR9009, SR9011, and insulins) from Section S4.4, and thyroid hormones