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Goeke J.E., Kist S., Schubert S., Hickel R., Huth K.C., Kollmuss M

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These aldehydes modify critical proteins via adduct formation, alter intracellular signaling, and promote the activation of NF-B and other pro-inflammatory pathways [34,35], which exacerbate local inflammation and contribute to the systemic oxidative burden observed in psoriatic patients [36]

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