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FIGURE 9 Discussion Hyperglycemia-induced chronic inflammation and metabolic dysregulation play a crucial role in the micro- and macro-vascular complications of diabetes and are associated with long-term dysfunction of various organs, especially the liver and kidneys ( Despite the benefits of pharmacological therapies, prophylactic approaches such as physical exercise, besides caloric restriction are considered the cornerstone in the management of type 2 diabetes ( Our previous study in GK rat pancreas demonstrated exercise-induced beneficial effects by improving energy metabolism, antioxidant responses and mitochondrial functions, and metabolic adaptation ( via the AMPK/SIRT-1/PPAR- signaling pathways

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[Google Scholar] 7.Aguilar-Toal J.E., Hernndez-Mendoza A., Gonzlez-Crdova A.F., Vallejo-Cordoba B., Liceaga A.M

Theriogenology 186 , 111 (2022)

My energy level is about the same