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Clinical presentations of coenzyme q10 deficiency syndrome

Anastasov N, Hfig I, Vasconcellos IG, Rappl K, Braselmann H, Ludyga N, et al

General symptoms include mid-day energy drop, drowsiness and poor exercise recovery

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Various therapeutic surgical modalities

More recently, NAC, titrated to a maximum dose of 2,400 mg over four weeks, failed to show significance over placebo in 35 pediatric TTM patients (aged 817 years).76) The authors noted that given that an improvement was seen in both groups, particularly in the first few weeks of treatment, the regular supportive assessments by the clinicians (every two weeks) and adjunctive psycho-education could have been responsible for strengthening the placebo effect