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TMAO can be ingested directly from TMAO-containing foods, such as seafood or fish[11], and it can be generated from the oxidation of TMA that occurs in the gut microbiota

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In addition to the rapid epigenetic modulation of glutamatergic function, preclinical studies showed that boosting mitochondrial metabolism of LAC protects against oxidative stress, rapidly ameliorates insulin resistance, and reduces neuroinflammation by decreasing proinflammatory pathways such as NFkB in hippocampal and cortical neurons

Since 1947, BHA has been incorporated into edible fats and foods containing fats due to its antioxidant qualities, which help prevent rancidity and the development of unpleasant odors in food (Lam et al