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Supplementation with L-glutathione may uphold the body's detoxification processes during pregnancy

Due to their multicomponent nature and multitargeted and synergistic effects, it is extremely challenging to study the specific molecular mechanism of herbal medicine to alleviate APAP-induced liver injury

World Psychiatry 2021;20:34-51

As MOTS-c activates AMPK and NRF2, it also indirectly suppresses the mTOR (mechanistic target of rapamycin) pathway, the master growth and anabolism regulator that, when chronically overactivated, accelerates the accumulation of senescent cells

2,3-bisphosphoglycerate is produced from the glycolytic intermediate 1,3-bisphosphoglycerate in the first of the two steps of the Rapoport-Luebering shunt

This dissociation suggests that some prosocial effects of oxytocin may be mediated by downstream metabolites acting through noncanonical mechanisms beyond OXTR activation