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Description
doi: 10.1002/rmb2.12590 171

Folic acid is synthetic and must be converted: With MTHFR variants or high intake, unmetabolized folic acid can accumulate, and the clinical significance is still being studied
DOI:10.5772/INTECHOPEN.71547 Pedrajas, J

Folinic acid (Leucovorin) is a derivative of folic acid, and is FDA approved to decrease the toxic effects of methotrexate on rapidly dividing host tissues that include bone marrow and GI mucosa

Yes, many people find that taking both provides comprehensive support
Gullner et al
