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There is also a significant body of evidence suggesting that GSTM1 +/+ individuals gain greater cancer protection from consumption total cruciferous vegetables or broccoli compared to GSTM1 -/- variant carriers (25, 48, 49)

A possible mechanism for the up-regulation of NADPH oxidase activity under redox stress

doi: 10.1038/nrd4510 289

Epigenetic changes, including aberrant DNA methylation and histone modification, further contribute to altered gene expression and sustained oncogenic signaling [226,227]

Furthermore, gene expression differences between pre-treatment and post-treatment or resistant and sensitive cell populations can be established to screen for differentially expressed genes (DEGs)

Note: This table is for informational purposes