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Discovery of peptide ligands targeting a specific ubiquitin-like domain-binding site in the deubiquitinase USP11

Clinical observation on effect of scalp electroacupuncture for mild cognitive impairment

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Taking advantage of the analysis of X-ray structures and the information that we gained from our previous studies [16], we investigated the potential binding between C5aR1 and paclitaxel and identified three main binding sites of C5aR1, one orthosteric and two allosteric