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Although the evidence is compelling that cysteine S -conjugate -lyase reactions contribute to the nephrotoxicity of DCVC and other cysteine S -conjugates derived from halogenated alkenes, as noted earlier, the sulfoxides of the cysteine S -conjugate and mercapturates may be even more toxic than the cysteine S -conjugate (Lash et al., 1994, Lash et al., 2003, Werner et al., 1996)

209,530 Notably, AD is associated with mtDNA mutations and reduced copy numbers, while PD is closely linked to mtDNA deletions

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Furthermore, recombinant expression systems may not fully replicate the native conditions, potentially leading to altered or incomplete protein functionality

Dat betekent dat het bestaat uit drie aminozuren: glutamaat, cystene en glycine

doi: 10.3389/fcell.2020.574223