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Therapeutic approaches: effects of ESA administration in anemia The administration of EPO or ESAs is a common therapeutic approach applied to stimulate and support erythropoiesis, particularly in patients with anemia associated with end-stage renal disease (21), patients with nonmyeloid cancer on chemotherapy, patients with HIV treated with zidovudine (58), or patients undergoing an elective, noncardiac nonvascular surgery to reduce the need for allogeneic blood transfusions (55)

Aspirin is most effective when taken in the morning, approximately half an hour after breakfast, as this timing allows for higher blood concentrations, resulting in a longer duration of action and improved bioavailability

[DOI] [PubMed] [Google Scholar] 51.Owen K.Q., Jit H., Maxwell C.V., Nelssen J.L., Goodband R.D., Tokach M.D., Tremblay G.C., Koo S.I

2011), and enhancing the endogenous antioxidant capacity, including the upregulation of CAT, SOD, and GSH-Px activities (Augustyniak and Skrzydlewska 2010