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In preclinical studies, it has been estimated that about 20% of the total energy needs of the adult brain may be met by fatty acid oxidation occurring in astrocytes [33]
12 For the treatment of HCV genotype 1 infection, sofosbuvir is dosed at 400 mg once daily and given in combination with peginterferon alfa and ribavirin for 12 weeks
2011;17:PI15

These symptoms manifest as persistent negative thoughts and emotional disturbances impairing daily functioning
"NHV" refers to normal human volunteers