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while normal dietary intake is considered safe, the effects of high-dose parenteral administration are less well studied

For example, the FPR2 synthetic peptide agonist WKYMVm reduced the accumulation of myofibroblasts and macrophage infiltration in the bleomycin model of skin fibrosis ( in vitro cultured human synovial fibroblasts ( The anti-fibrotic actions of several specialized pro-resolving mediators (SPMs), which are bioactive molecules produced from essential polyunsaturated fatty acids, have also been tested using in vitro and in vivo models

Pathological studies with immunohistochemical and Western Blot analyses using Ki67 and pERK antibodies showed a potential effect of MEK inhibiting therapy

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Abstract Fibromyalgia, a chronic pain condition marked by abnormal pain processing, impacts a significant part of the population, leading to reduced quality of life and function