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By modulating this immunometabolic axis, GLP-1RAs may indirectly attenuate thyroid autoimmunity, supporting their potential role as dual-purpose agents in patients with coexisting metabolic and AITD

References 1 AdamuA.LiS.GaoF.XueG

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This M1 polarization leads to increased expression of pro-inflammatory markers (such as CD80 and CD86) and cytokines (like IL-1, IL-6, and IL-12), while reducing levels of immunosuppressive cytokines such as IL-10

Each layer is designed to work independently and to reinforce the others

Supplements that raise growth hormone (arginine, GABA, melatonin) could increase the chance of joint pain or swelling