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doi:10.1007/s10558-010-9092-1

Similarly, depletion of shmt2 promotes the accumulation of reactive oxygen species (ROS) by disrupting cellular redox status, although this effect was observed in bladder cells 70
Life 14, 9971010

In Vitro and Cellular Systems for the Characterization of Bioactivating and Inactivating Drug Metabolizing Enzymes in Adverse Drug Reactions
New Engl J Med (2011) 364(20):192031

However, this therapy does not lower the levels of the intermediate metabolite, GAA, seen with GAMT deficiency
