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For patients with Long COVID, ME/CFS, or dysautonomia, clinical guidelines generally suggest a total daily dosage ranging from 1,000 mg to 2,000 mg, divided into two or three doses taken throughout the day
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In rats with streptozotocin (STZ)-induced diabetes, eight-week treatment with insulin (NPH, 1.5 U/100gr/day) and melatonin (0.2 mg/kg/day in drinking water) improves glucose homeostasis and insulin sensitivity of white adipose tissue comparing with using one of these drugs individually [59]
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