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Moreover, a Cochrane review (i.e., pooled analyses of studies with stricter inclusion criteria) of three randomized controlled trials in children with moderate-to-severe asthma (115 children in total) found treatment with intravenous magnesium sulfate on top of standard therapy reduced hospital admission in children with acute asthma by 68% (95% CI, 0.14-0.74) (164)

and the Natural Sciences and Engineering Research Council of Canada (NSERC

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For example, elevated succinate oxidation in a cellular environment of few or no ATP generation induces a phenomenon described as reverse electron transport whereby electrons flow backwards along the ETC to complex I

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Polypharmacology in a single drug: Multitarget drugs