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( 10.1093/eurheartj/ehx342) [DOI] [PubMed] [Google Scholar] 17

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Acknowledgements This work was supported in part by grants from Fondo de Investigacin Sanitaria (www.isciii.es) (PI15/ 00713) and GEHEP-SEIMC (GEHEP-004)

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PBP1b and LpoB form a transient complex Given that LpoB-mediated activation is critical for PBP1b catalysis in vivo, we sought to explore how LpoB contributes to each step of the polymerization reaction by measuring LpoB binding to PBP1b in the presence of lipid II substrate and glycan chain intermediates

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