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The core challenge lies in how to deliver drugs precisely and efficiently to the target while ensuring safety
CRHR1 mediates the transcriptional expression of pituitary hormones and their receptors under hypoxia
Since CPP-CAND was designed to interfere with the FOXO4-p53 interaction, we investigated the disruption of FOXO4-p53bp1 foci in the nucleus of senescent cells after CPP-CAND treatment
Additional file 6: Figure S2
Crosstalk between microbiota-derived short-chain fatty acids and intestinal epithelial HIF augments tissue barrier function
The concept of synergistic therapy is common in medicine, but it requires careful study to ensure that the combination is both safe and more effective than either compound alone
