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Mangiferin directly binds to Keap1, activates the downstream Nrf2/SLC7A11/GPX4 pathway, inhibits osteoblast ferroptosis, promotes bone formation and improves osteoporosis in ovariectomized mice and iron overload mice
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NPJ Vaccines 8:79 Mitzel DN, Wolfinbarger JB, Long RD, Masnick M, Best SM, Bloom ME (2007) Tick-borne flavivirus infection in Ixodes scapularis larvae: development of a novel method for synchronous viral infection of ticks

The -KG supplement group showed opposite changes (Fig

doi: 10.3390/biom11070923 150 ZhangS.LachanceB
