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3.3.2 Intracellular GSH Level Elevation In vitro studies demonstrate that SAG effectively replenishes intracellular GSH pools across various cell types, particularly in cellular models with impaired endogenous GSH synthesis

Polishchuk EV, Merolla A, Lichtmannegger J, Romano A, Indrieri A, Ilyechova EY, et al

SAM is a methyl group donor for numerous methylation reactions in the brain, including those involved in the metabolism of neurotransmitters whose deficiency has been related to depression (102)

In cystinosis, mutations in the gene for cystinosin give rise to the lack of a functional lysosomal cystine transporter (43)

However, it falls under NPRA (National Pharmaceutical Regulatory Agency) regulation as a pharmaceutical product
