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NE and SD: writingreview and editing

In that sense, while still representing a challenging goal to be achieved, the identification of specific prognostic biomarkers and also those for the evaluation of therapeutic efficacy in ALS will have a fundamental role in designing and monitoring new treatment strategies in the complex scenario of the neurodegenerative process

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Hitting the same spot repeatedly creates scar tissue and chronic irritation

Headache or fatigue: Occasionally reported, usually resolving without intervention