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Specific amino acids, such as glutamine, arginine, taurine, tryptophan, and methionine, are highlighted for their multifaceted roles in stress physiology, including immune modulation, antioxidant defence, osmoregulation, and neurotransmitter synthesis

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Elevated plasma vitamin B12 has been associated with solid cancers, based on a single B12 measurement

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The review also addresses the role of SAM as a non-consumable cofactor in enzymatic processes, highlighting its function as a prosthetic group for certain protein enzymes and its ability to form complexes with ribozymes

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