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When the damage is minor or non-repetitive, wound healing is efficient, but when the injury is repetitive or the resolution is improper, components of the ECM continue to accumulate, leading to permanent scarring, disruption of tissue architecture, and organ dysfunction [8]

doi: 10.15252/embj.2022112012

Ramifications of reducing iron-overload via iron chelation in a highly metabolically active tissue was evidenced in a limb ischemic reperfusion mouse model

Large-scale quantitative proteomics identifies the ubiquitin ligase Nedd4-1 as an essential regulator of liver regeneration

Researchers identified a short FOXO4p53 interaction region and converted it into a D-retro-inverso peptide to improve stability and cell permeability

Kangxi, only 7 years old, had been chosen over his older brother because Kangxi had already survived smallpoxan epidemic that was cutting a scythe through the ruling elite