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The levels of GSH and MDA were estimated by the methods which were described by Beutler et al., [11] and Buege et al., respectively [12]

doi: 10.1155/2019/5613417 217 XiongJWangDWeiAKeNWangYTangJet al

We conclude that SBM-based diets did not provide adequate glycine for the syntheses of creatine and GSH in growing Phase-I or Phase-II HSB and that dietary supplementation with 1% or 2% glycine is necessary for the maximal growth and feed efficiency, as well as the optimal health (including intestinal health) of these aquatic animals
We demonstrated that the accumulated fumarate leads to oxidative stress by covalently binding to reduced GSH in a non-enzymatic reaction that forms succinicGSH
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In addition, molecular analyses identified CYSLTR1 and PTH1R as probable molecular targets of PP-NPs, suggesting receptor-mediated pathways as key contributors to the observed neurotoxicity [94]