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Several studies also indicated that the neuroprotective effect of lycopene could be related to the emendation of mitochondrial disfunction and neuroinflammation reduction, such as Sandhir et al., which investigated the neuroprotective effect of lycopene on an in vivo model of 3-nitropropionic acid-induced mitochondrial dysfunctions and oxidative stress [118]
SFNs activation of the Nrf2-ARE signaling pathway was found to improve neurological dysfunction after ICH [30]
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