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Piccoli A, Cannata F, Strollo R, et al
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Pharmacokinetics, safety, and tolerability of oral semaglutide in subjects with hepatic impairment
A GPCR negative feedback model recapitulates fine dynamic responses of wt and tax6 mutants The above experiments position calcium and TAX6/Calcineurin as key components for GPCR inhibition and exact adaptation
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