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G(12) overexpression in hepatocytes by ER stress exacerbates acute liver injury via ROCK1-mediated miR-15a and ALOX12 dysregulation

The TGF-1/Smad3 pathway is a key driver of this process, inducing the expression of fibrotic markers such as -SMA and collagen I, promoting interstitial remodeling

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BPC-157 in subkutaner oder lokaler Anwendung wird hier zunehmend als adjuvante Therapie eingesetzt, oft in Kombination mit physiotherapeutischen Standard-Protokollen

PHGDH knockdown in estrogen receptor-positive (ER + ) breast cancer cells exposed to cytotoxic chemotherapy (carboplatin or doxorubicin) results in increased mitochondrial ROS and prevents chemotherapy-induced enrichment of cancer stem cells (CSCs) (128)

10.1016/j.jneumeth.2011.06.019 110 KhanK.Factor-LitvakP.WassermanG