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Preclinical studies have shown that inhibiting mitophagy or restoring MPC function can effectively suppress tumor cell viability and synergize with conventional chemotherapeutics such as 5-FU and oxaliplatin [48, 50]

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Retinal development is characterized by the differentiation of neural progenitor cells (NPCs) into various retinal cell types (Figure 1D), a process tightly regulated by DNA methylation, enabling the transition of the retina from embryonic to mature stages (Singh et al., 2017

These results appear to contradict finding reported in vivo (Payabvash et al., 2006)