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International Diabetes Federation, 7th edn

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Concerning CYP1A2, in vivo induction is suggested, as demonstrated by the paraxanthine-to-caffeine ratio rising in healthy subjects ( In light of these findings, the safety and efficacy profile of RIF during TB treatment can be altered in smokers because of the concomitant induction of CYP450 enzymes mediated by PAHs

The correlation analysis indicated that the basal (prior to irradiation) pulmonary levels of GPx2 mRNA as well as GPx activity positively correlated with the post-irradiation asymptomatic survival time of mice