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Obese rats fed with a high-fat diet weighed more initially (588.7 14.1 g) than rats on a standard chow diet (497.8 15.1 g, p 0.05, n.s.)

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In a subset of rats sacrificed 30 min post-SPS, IN-NPY significantly reduced elevations of adrenocorticotrophic hormone (ACTH) and corticosterone, and attenuated the induction of tyrosine hydroxylase (TH

The KEGG (Kyoto Encyclopedia of Genes and Genomes) pathway analysis enriched many pathways involving nitrogenous metabolites (Fig

It is worth considering that ketogenic diets, being extreme diets with a very high fat content, may negatively affect blood lipids, leading to elevated triglycerides and cholesterol, which increase the incidence of cerebral infarction and heart disease (20)

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