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Mayo Clinic

This is particularly valuable for athletes and active individuals who require adequate caloric intake to support training demands, for those following specific dietary protocols that rely on intact hunger cues, or for anyone seeking body composition improvements without the complications of appetite manipulation

Most of the evidence giving rise to this claim comes from a few observational studies

First, a bacterial reverse mutation test (Ames test) assessed AOD9604s mutagenic potential using four histidine-dependent auxotrophic mutants of Salmonella typhimurium (TA1535, TA1537, TA98, TA100) and one tryptophan-dependent auxotrophic mutant of Escherichia coli (WP2 uvrA), using both plate incorporation and pre-incubation methods at doses of 0, 1.6, 8, 40, 200, 1,000, and 2,000 g AOD9604/plate

Drug Categories Experimental metabolic modulator, NNMT inhibitor, anti-obesity agent, muscle regenerative enhancer