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In another study, nicotinic acid affected the hepatic uptake of ApoAI lipoprotein, thereby reducing high-density lipoprotein (HDL) removal from the circulation (reviewed in 20)
These preliminary findings urge future in-depth studies on how to modulate Klotho expression through dietary interventions to improve DKD

Experimental literature has also investigated VEGF and VEGFR2 signaling, growth hormone receptor expression in tendon fibroblasts, neurotransmitter modulation, and neuroprotective pathways involving the dopaminergic and serotonergic systems
Biomed Pharmacother 91:645655

Bidirectional brainheart interactions in health and disease

Fisher A, Pittel Z, Haring R, Bar-Ner N, Kliger-Spatz M, Natan N, Egozi I, Sonego H, Marcovitch I and Brandeis R (2003) Ml muscarinic agonists can modulate some of the hallmarks in Alzheimer's disease: implications in future therapy
