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In humans, bone marrow, spleen, lymph node, thymus, and gastrointestinal tract from the stomach through the colon, sparing the esophagus, are the only tissues in which eosinophils normally reside.38 Furthermore, the gastrointestinal tract is the only organ other than bone marrow in which extracellular eosinophil granule protein deposition is observed even under homeostatic conditions

ACS Pharmacol Transl Sci 3:749758

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In STZ-induced DN rats, Mulberry leaf tea markedly ameliorated hyperglycemia and renal injury by restoring the abundance of Adlercreutzia , Anaerofustis , Coprococcus , Dorea , Roseburia , Oscillospira , Phascolarctobacterium , Coprobacillus , Sutterella and RF39 , which indicated that Mulberry leaf tea can be used as a dietotherapy for DN therapy through gutkidney axis (Sheng et al., 2018)

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