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By interacting with the outer membrane protein voltage dependent anion channel (VDAC), HK protects the normal function of the mitochondrial outer membrane and maintains the balance between pro-apoptotic proteins and anti-apoptotic proteins, prevents the release of Cyt-C, and enhances cell proliferation and inhibits apoptosis (62)

Nature 582 , 246252 (2020)

19,96 Restoration of SIRT1 activity suppresses lipid synthesis, improves oxidation capacity, and reestablishes lipid clearance, supporting therapeutic strategies aimed at metabolic reprogramming in MASLD

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At birth, the lung undergoes a dramatic change from a fluid-filled to a gas-filled organ, thereby subjecting the neonate's lung to a transition from a relatively hypoxic environment to one that is hyperoxic (1015% O 2 ) [5, 8, 10, 19, 20]
