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K-means clustering analysis of amplicon sequence variants by animal demonstrated that NNMTi-treated DIO mice switched to LD had a distinct microbiome pattern that was highlighted by decreased Erysipelatoclostridium and increased Lactobacillus relative abundances compared to vehicle counterparts

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5-AMINO-1MQ is a Small-molecule NNMT inhibitor (not a peptide) studied for body-composition and insulin-sensitivity