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381,382,383,384 They are easily synthesized, possess relatively stable chemical properties, and exhibit a high selectivity

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Besides upregulation of anti-oxidative stress capacity, another mechanism by which FoxO activation or low insulin drive may reduce oxidative stress includes the activation of Peroxisome Proliferator-activated receptor Gamma Coactivator 1 (PPGC-1), a nutrient sensing system that shifts substrate utilization towards fat and away from carbohydrate and increases mitochondrial biogenesis [66]

Diabetes 67 , 17611772 (2018)

2015;8:Cd010497

Allen M, Huang BS, Notaras MJ, Lodhi A, Barrio-Alonso E, Lituma PJ et al (2022) Astrocytes derived from ASD individuals alter behavior and destabilize neuronal activity through aberrant Ca2+ signaling