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Based on available data, no adjustment of STIOLTO RESPIMAT dosage in geriatric patients is warranted [see Clinical Pharmacology (12.3)]

3 On the other hand, an excessive amount of ROS may promote cellular damage, leading to cell death by regulating certain signaling cascades
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2000;348(Pt 3):60714

Suvarna et al., 2021

Signant Health's RTSM capabilities manage the randomization, dispensing, and supply chain logistics of investigational products across investigative sites and direct-to-patient shipment channels providing an integrated DCT supply chain management function that bridges the operational gap between centralized drug supplies and decentralized participant delivery locations
