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Superoxide anions mainly damage biological membranes, causing lipid peroxidation that generates cytotoxic secondary products of lipid oxidation

[DOI] [PMC free article] [PubMed] [Google Scholar] 163.Leenay R.T., Vento J.M., Shah M., Martino M.E., Leulier F., Beisel C.L

Insulin Resistance, Affective Disorders, and Alzheimers Disease: Review and Hypothesis

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For example, PAE not only protects against AS but also exerts neuroprotective effects by inhibiting neuronal ferroptosis in cerebral hemorrhage (Jin et al., 2021) and serves as an antidepressant (Wei et al., 2023)

2019;20 doi: 10.3390/ijms20184359