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Ipamorelin produces GH release without significant changes in these other hormones at research-effective doses

5 Metformin promotes apoptosis of glioma cells Metformin has recently gained attention for its potential antitumor effects, particularly in various cancer types, including glioblastoma (34)

For example, HIFs have been shown to induce glycolytic enzymes, allowing cells to adapt their carbohydrate metabolism during hypoxia 23

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Notably, metformin also causes unfavourable side effects, for example, increased relative abundance of Escherichia spp

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