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GJS, SB, and SPH were partly supported by the Research Council of Norway through its Centres of Excellence funding scheme (project number 262613), and financial support from UiO:Life Science (Project MORGI-20493) is gratefully acknowledged

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For more information regarding the calculation of DA/H see Aerodrome Operating Minima (AOM)

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The mechanistic relevance of these matrix observations is often tied back to copper coordination: several cuproenzymes participate in the maturation and cross-linking of connective-tissue proteins, so a copper carrier that improves the availability of the metal to those enzymes offers one internally consistent link between the coordination chemistry and the reported matrix effects