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In this assay using human Capan 1 cells, the cyclic proteins behaved similarly to the reference protein K1B in the concentration range tested (10 pM100 nM) by their capacity to induce a mesenchymal-like phenotype and cell scattering

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doi: 10.1016/j.ijpharm.2011.02.062

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They can be injected in the same session (separately drawn up, separate syringes), but never mix in the same vial

In the case of nitrogen, this effect is partly driven by the increased demand in glutamate to sustain photorespiratory metabolism due to both the direct involvement of 2-oxoglutarate/glutamate cycling and the slight incompleteness of glycine-to-serine production, which must be compensated for by an increased N assimilation 37