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Rauschecker and colleagues (166) have proposed the frontostriatial gating theory of tinnitus that posits that the nucleus accumbens (NAc) and the ventromedial prefrontal cortex (vmPFC) are central parts of a network that evaluates the relevance and affective value of internally generated tinnitus percepts (FIGURE 6)

Surgery was performed only on the right ear of each animal and was completed within 510 min

Johnston PA, Soares KM, Shinde SN, Foster CA, Shun TY, Takyi HK, Wipf P, Lazo JS (2008) Development of a 384-well colorimetric assay to quantify hydrogen peroxide generated by the redox cycling of compounds in the presence of reducing agents

Furthermore, it counteracts also gastric and liver lesions, induced by acute or chronic administration of alcohol (13, 20)

While elevated intraocular pressure (IOP) is a primary risk factor, it is not the sole etiological factor, as glaucoma can develop even in the presence of normal IOP levels [131,132,133]

Small fiber neuropathy in hypermobile Ehlers Danlos syndrome/hypermobility spectrum disorder