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The suppressed cell proliferation and induced cell cycle arrest collectively contribute to inhibited tumor growth in melanoma xenograft models (Feng et al., 2021)

Cancer and drug-resistant tumors Resistance to commonly used alkylating agents or platinum chemotherapeutic drugs is often multifactorial, involving altered drug transport, biotransformation and enhanced detoxification capacity (Lu, 1999a)

B12 injections are typically given monthly, and telehealth makes them more accessible

Treatment should always be individualized

doi: 10.1016/s0928-4257(01)00036-5

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