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FBXW7 contributes to circadian rhythmicity by targeting mTOR, a key regulator of circadian translation, for ubiquitin-mediated degradation, resulting in opposing oscillations between FBXW7 and mTOR protein levels and enabling rhythmic control of translational output (Okazaki et al., 2014

94 Abnormal activation of the Wnt/-catenin pathway occurs in IPF fibroblasts, which stimulates the proliferation of mesenchymal cells and promotes the process of fibrosis

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14a, b)

Higher concentration of LPS had been also found in STEMI patients, but not in stable CAD subjects and healthy controls [63]

The big revolution has come in the field of imaging, where convolutional neural networks have either matched or outperformed radiologists in mammogram interpretation