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For visible skin brightening, a series of 612 sessions is usually recommended, with results building over 48 weeks depending on your starting skin tone and treatment frequency

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Future efforts should utilize in vitro dynamic models (such as the hollow-fiber infection model) and animal models to comprehensively understand the PK/PD properties of drugs, thereby enabling dosing regimens that provide maximal synergy while minimizing toxicity and resistance development (Wale et al., 2024)

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